Evolute CX, A Mixed-mode Resin-based SPE Sorbent, For Extraction Of Basic Drugs From Biological Fluids Using Generic Procedure

Main Category: Biology / Biochemistry
Also Included In: Pharma Industry / Biotech Industry;  Pharmacy / Pharmacist
Article Date: 17 Mar 2008 - 3:00 PDT

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Biotage introduces the new EVOLUTE® CX sample preparation range - EVOLUTE CX is a mixed-mode resin-based SPE sorbent for the extraction of basic drugs from biological fluids using a generic procedure, minimizing method development time for bioanalysts. EVOLUTE CX removes protein, phospholipids, and salt interferences, delivering cleaner extracts with high reproducibility for accurate quantitation and trouble-free analyses through pre-clinical and clinical trials.

Biotage's EVOLUTE CX uses a combination of robust polymer chemistry, uniform coverage of sulfonic acid (SO3-) groups and optimum exchange capacity to provide greater than 85% recovery on a broad range of sample matrices. The surface characteristics of every batch are tested to ensure consistency. A combination of optimized pore size, sorbent chemistry and associated generic method results in extremely clean extracts for LC-MS/MS.

The Biotage EVOLUTE family of products now includes EVOLUTE ABN (30µm and 50µm) and EVOLUTE CX. EVOLUTE products provide highly effective solutions to the problems of ion suppression and matrix effects from dirty extracts. These high performance products allow scientists to use a generic approach for a wide range of compounds, reducing method development time while improving extract cleanliness.

Biotage offers a wide range of sample preparation tools for Bioanalytical, Clinical, Environmental, Food and Forensic applications. With a variety of sorbent chemistries and formats, IST sorbents deliver cleaner extracts with higher analyte recovery for precise analysis.

For more information on Biotage's EVOLUTE CX sample preparation products, please visit booth #2934 at PITTCON 2008, from 1-7 March 2008. Alternatively please email product_info@biotage.com or visit www.biotage.com

About Biotage

Biotage is a global company active in life science research with strong technologies, a broad range of operations and a long-term view of the market. The company offers solutions, knowledge and experience in the areas of genetic analysis and medicinal chemistry. Customers include the world's top 30 pharmaceutical companies, 20 largest biotech companies and leading academic institutes. The company is headquartered in Uppsala and has offices in the US, Japan, UK and several other European countries. Biotage has approx. 330 employees and had pro-forma sales of approx. 500 MSEK in 2004. Biotage is listed on the Stockholm stock exchange. Website: http://www.biotage.com