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Alcohol / Addiction / Illegal Drugs News

Pharmacology Of Crystal Meth

Main Category: Alcohol / Addiction / Illegal Drugs
Article Date: 16 Jun 2008 - 17:00 PDT

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When smoked, crystal meth rapidly achieves high concentrations in the brain without the burdens of the intravenous route. Kish reviews the actions of methamphetamine and explains the potential role of dopamine in methamphetamine craving.

The author states that there is no medication approved for the treatment of relapses of methamphetamine addiction, but potential therapeutic agents targeted to dopamine and non-dopamine systems are in clinical testing.

"Research into the pharmacologic treatment of methamphetamine addiction has largely been limited to studies in animals," states Kish. "Although animal studies are essential to the development of new medications, given the public health importance of this worldwide problem and the existence of potential drug targets, it is obvious that the very slow pace of clinical testing of new therapies in methamphetamine addiction needs to be accelerated."

Prevention, treatment, enforcement and harm reduction form the 4 pillars of the York Region's strategy to combat methamphetamine. In their article, Cronkwright, Kirkos and colleagues recognize that criminal behavior is only one element in the production and use of methamphetamine, and they identify elected officials, school boards, the courts, at-risk communities and private industry as key stakeholders in the strategy.

About the Canadian Medical Association Journal (CMAJ)

CMAJ
is the leading health sciences journal in Canada. CMAJ is a general medical journal publishing original research and review articles, commentaries and editorials, practice updates, an arts and ideas section and health news. Published continuously since 1911, new issues are uploaded on http://www.cmaj.ca every second Monday at 4:30 p.m. EST/EDT. http://www.cmaj.ca contains the complete editorial contents of CMAJ, supplemented by a variety of interactive features and additional content.

Canadian Medical Association Journal




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