ORLANDO, FL (UroToday.com) – Data is emerging about use of statins and risk reduction in development of prostate cancer (CaP). How do statins affect PSA?
The authors previously observed that PSA levels decreased upon initiation of statin medications.
In this report Hamilton and colleagues examined influence of statin drugs on PSA velocity in healthy men. 305 male veterans who did not have prostate cancer, who were prescribed a statin between 1994 and 2006, and who had an adequate number of PSA values on record (at least 2 values before and after the start of statins) were included in the analysis.
PSA values before and after the start of statins were compared. With statin use, median decline in PSA levels was 5.9% (p
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