KAI-1 Able To Distinguish Chromophobe Renal Cancers From Oncocytoma

Main Category: Urology / Nephrology
Also Included In: Cancer / Oncology
Article Date: 05 Jul 2008 - 0:00 PDT

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ORLANDO, FL (UroToday.com) - (Reported from the Annual Meeting of the American Urological Association) Researchers showed that KAI-1 can differentiate chromophobe renal cancers from oncocytoma.

Papillary renal cancer with clear cell components is worse than pure papillary tumors.

There was a general trend toward watching small renal masses rather than surgery. Small renal tumors that are destined to be metastatic have a growth rate of 0.74cm/year compared to 0.29cm/year for benign masses.

Patients with multiple tumors in one kidney should undergo partial nephrectomies rather than a radical nephrectomy because there is a high risk the contralateral kidney will develop cancer.

Positive surgical margins on frozen section after a partial nephrectomy does not necessarily lead to a local recurrence. Completion nephrectomy should not be done if a focal positive margin is found on the resected renal mass.

Presented by Edward Messing, MD, at the Annual Meeting of the American Urological Association (AUA) - May 17 - 22, 2008. Orange County Convention Center - Orlando, Florida, USA.

Reported by UroToday.com Contributing Editor David P. Wood, MD

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