Decreasing Radiographic Screening Burden Of Testis Cancer Patients

Main Category: Urology / Nephrology
Also Included In: Cancer / Oncology;  Radiology / Nuclear Medicine
Article Date: 06 Jul 2008 - 6:00 PDT

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ORLANDO, FL (UroToday.com) - (Reported from the Annual Meeting of the American Urological Association) The main thrust of the presentations concerned decreasing the radiographic screening burden of patients with testis cancer.

Chamin, et al, used SEER data to evaluate the risk of secondary malignancy in men with testis cancer who did or did not have a RPLND. After 14 yrs follow-up, men on a surveillance protocol for their testis cancer had a 1.69 times higher risk of a second malignancy. Radiation associated malignancies were 1.9 times higher in the surveillance group.

Yu determined that the compliance of radiographic and marker surveillance was poor and overtime the compliance worsened. Compliance was better in men who had previously undergone a RPLND.

Kakiashvili showed that RPLND at the time of relapse in men on a surveillance protocol was effective and the same as men who opted for an immediate RPLND.

Finally, Nicolai evaluated risk factors for distant metastases after RPLND. Vascular invasion in the primary tumor and the pT stage were the best predictors of distant metastases. Nodal disease and tumor type were not predictive.

Presented by Richard Bihrle, MD, at the Annual Meeting of the American Urological Association (AUA) - May 17 - 22, 2008. Orange County Convention Center - Orlando, Florida, USA.

Reported by UroToday.com Contributing Editor David P. Wood, MD

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