A New-Generation Of Simpler Sensors For Detecting Disease-Causing Microbes And Toxins

Main Category: Medical Devices
Also Included In: Infectious Diseases / Bacteria / Viruses;  Biology / Biochemistry
Article Date: 19 Jul 2008 - 0:00 PDT

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Scientists in Singapore are reporting development of a complete, palm-sized sensor that can detect disease-causing microbes, toxins, and other biological threats instantly without the need for an external power source or a computer. The long-awaited device, ideal for remote medical clinics, battlefields, and other sites, represents the next-generation of faster, simpler biosensors, according to a study scheduled for the August 1 issue of ACS' Analytical Chemistry, a semi-monthly journal.

In the new study, Pavel Neuzil and Julien Reboud explain that the new device uses an existing method for detecting DNA, proteins or cells based on their interaction with light shown on the nanostructured surface when these materials come into contact with it. Most existing biosensors of this type require the use of an external power source, a complex and costly analyzer and rely on an external personal computer to report the results.

Their self-contained analyzer relies on simpler components, such as four light-emitting diodes (LEDs) that light up in specific patters to produce test results without a computer, the researchers say.

"Palm-Sized Biodetection System Based on Localized Surface Plasmon Resonance"
Pavel Neuzil and Julien Reboud
ASAP Anal. Chem., ASAP Article, 10.1021/ac800335q
Click here to view Abstract online

American Chemical Society
www.acs.org