Individual Tumorigenesis Pathways Of Sporadic Colorectal Adenocarcinomas Linked To The Biological Behaviors Of Tumors

Main Category: Cancer / Oncology
Article Date: 24 Jul 2008 - 1:00 PST

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Particular pathways of colorectal tumor growth are closely associated with characteristic pathologic features which, in turn, determine biological behaviors such as tumor growth, invasion and recurrence.

This study compared data of 244 colorectal cancer patients who had curative surgery and examined their known genetic changes to determine the associated tumorgenesis pathways in sporadic colorectal cancer.

This novel approach of compiling genetic and molecular alterations present researchers with an opportunity to select recurrence-prone patients for strict follow-up treatments after curative operations.

"Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behaviors of tumors"
Jin C. Kim, Young K. Cho, Seon A. Roh, Chang S. Yu, Gyungyub Gong, Se J. Jang, Seon Y. Kim, Yong S. Kim
Cancer Science Volume 99 Issue 7, Pages 1348 - 1354
DOI 10.1111/j.1349-7006.2008.00819.x
Click here to view Abstract online

About Cancer Science

Cancer Science (formerly Japanese Journal of Cancer Research) aims to present research that has a significant clinical impact on oncologists or that may alter the disease concept of a tumor. The Journal publishes original articles and editorials, letters to the editor, review articles and reports describing original research in the fields of basic, translational and clinical cancer.

Subject categories include:
-- carcinogenesis
-- tumor biology and pathology
-- molecular biology and genetics
-- epidemiology and prevention
-- immunology and virology
-- experimental therapeutics
-- clinical medicine

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