A Killer-Rescue System For Self-Limiting Gene-Drive Of Anti-Pathogen Constructs

Main Category: Biology / Biochemistry
Also Included In: Tropical Diseases;  Genetics
Article Date: 03 Sep 2008 - 3:00 PDT

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One of the concerns of citizens with the development and use of genetically engineered mosquitoes in the fight against dengue fever and malaria is the fact that most of the current approaches result in released engineered strains remaining in the environment.

We provide a novel approach that enables self-limiting spread of an engineered construct and describe its population genetic and mechanical properties.

Proceedings of the Royal Society B: Biological Sciences

Proceedings B is the Royal Society's flagship biological research journal, dedicated to the rapid publication and broad dissemination of high-quality research papers, reviews and comment and reply papers. The scope of journal is diverse and is especially strong in organismal biology.

Proceedings of the Royal Society B: Biological Sciences