How To Diagnose Biliary Atresia With Ultrasonic Technique?

Main Category: GastroIntestinal / Gastroenterology
Also Included In: MRI / PET / Ultrasound
Article Date: 26 Sep 2008 - 5:00 PDT

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Biliary atresia (BA) is a common progressive and obstructive pathological change of the intrahepatic and extrahepatic duct, often causing cirrhosis immediately and leading to death. Prompt and accurate early diagnosis determines its optimal operation opportunity and therapeutic efficacy. With the unceasing updating of ultrasonic apparatus, especially the application of high resolution detecting head, the sonogram is becoming more and more clear, and more and more doctors have investigated and accumulated experiences in the ultrasonic diagnosis for BA. However, there have been no general and unitive diagnostic criteria up to now.

A research article published on 14 June 2008, in the World Journal of Gastroenterology addresses this question. By cross section scan of the right branch of portal vein, it can be seen that the triangular cord adhered tightly to its right anterior area. Cross section scan of the right branch of portal vein was easier to show the triangular cord compared with longitudinal section scan, making it easier to be mastered by learners.

The triangular cord can be observed at the porta hepatis (thickness: 0.3 cm-0.6 cm) in 10 patients with biliary atresia. Smaller triangular cord (0.2 cm-0.26 cm) can be observed in 3 cases. The gallbladder was not observed in 2 cases, and 1 case showed streak gallbladder without capsular space. The gallbladders of 15 cases were flat and small. The gallbladders of 2 cases were of normal size and appearance, however, there was no postprandial contraction. The livers of all cases showed hepatomegaly and hetreogeneous echogenicity. Statistical analysis was performed to compare hepatomegaly and hetreogeneous echogenicity and the stage of hepatic fibrosis.

The present study considered that the presence of the triangular cord at the porta hepatis was specific, However, it was not the only diagnostic criteria, since flat and small gallbladder and poor contraction were also of important diagnostic and differential diagnostic significance. The degree of hepatomegaly and hetreogeneous echogenicity was proportional with liver fibrosis, and was able to indicate the duration of course and prognosis.

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Article adapted by Medical News Today from original press release.
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Reference: Li SX, Sun M, Zhang Y, Shi B, Xu ZY, Huang Y, Mao ZQ. Ultrasonic diagnosis for biliary atresia: A retrospective analysis of 20 patients. World J Gastroenterol 2008; 14(22): 3579-3582 http://www.wjgnet.com/1007-9327/14/3579.asp

Correspondence to: Shi-Xing Li, Department of ultrasound, Shengjing Hospital of China Medical University, No.36, Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China.

About World Journal of Gastroenterology

World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection and provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and Hepatology, CAB Abstracts and Global Health. ISI JCR 2003-2000 IF: 3.318, 2.532, 1.445 and 0.993. WJG is a weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th day of every month. WJG is supported by The National Natural Science Foundation of China, No. 30224801 and No. 30424812, and was founded with the name of China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998.

About The WJG Press

The WJG Press mainly publishes World Journal of Gastroenterology.

Source: Lai-Fu Li
World Journal of Gastroenterology