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Fertility News

Notion That Eating A Certain Cereal Will Result In More Male Babies Refuted By Paper

Main Category: Fertility
Also Included In: Nutrition / Diet
Article Date: 14 Jan 2009 - 2:00 PDT

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Researchers S. Stanley Young, Ph.D., Assistant Director of the National Institute of Statistical Sciences, Heejung Bang, Ph.D., of Cornell University and Kutluk Oktay. MD, FACOG, Professor of Obstetrics & Gynecology and Director, Division of Reproductive Medicine & Infertility Department of Obstetrics & Gynecology from New York Medical College, wrote a paper, "Cereal-Induced Gender Selection? Most Likely a Multiple Testing False Positive," which has been published in the January 14, 2009 online issue of the Proceedings of the Royal Society B. The paper questions the claims made by Mathews, Johnson and Neil (2008) in their article "You are What your Mother Eats" that was published in the April 22, 2008 Proceedings of the Royal Society B, and generated over 50,000 Google hits due to media interest.

Young, Bang & Oktay note that the original research by Mathews, Johnson & Neil implied that children of women who eat breakfast cereal are more likely to be boys than girls. Young, Bang & Oktay assert that the result of the original study is easily explained as chance. Young, Bang & Oktay examined the data sets from the original study and noted that 132 food items were tested for two time periods, totaling 264 statistical tests.

With this many tests, it is quite likely that some apparent statistical significance will occur simply by chance.

At the standard significance level of 5% (that is, there is 5% chance that the data will show an effect even when there is none), the 264 tests will yield approximately 13 false positives unless the analysis is adjusted to account for multiple testing. Young, Bang & Oktay argue that this is precisely what happened.

"This paper comes across as well-intended, but it is hard to believe that women can increase the likelihood of having a baby boy instead of a baby girl by eating more bananas, cereal or salt. Nominal statistical significance, unadjusted for multiple testing, is often used to lend plausibility to a research finding; with an arguably implausible result, it is essential that multiple testing be taken into account with transparent methods for claims to have any level of credibility," note Young, Bang & Oktay.

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Article adapted by Medical News Today from original press release.
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About NISS

The National Institute of Statistical Sciences was established in 1990 by the national statistics societies and the Research Triangle universities and organizations, with the mission to identify, catalyze and foster high-impact, cross-disciplinary and cross-sector research involving the statistical sciences. NISS is dedicated to strengthening and serving the national statistics community, most notably by catalyzing community members' participation in applied research driven by challenges facing government and industry. NISS also provides career development opportunities for statisticians and scientists, especially those in the formative stages of their careers. NISS is located in Research Triangle Park, North Carolina.

For more information about the NISS, go to http://www.niss.org/.

About The Royal Society

The Royal Society is an independent academy promoting the natural and applied sciences. Founded in 1660, the Society has three roles, as the UK academy of science, as a learned Society, and as a funding agency.

It responds to individual demand with selection by merit, not by field. As we prepare for our 350th anniversary in 2010, we are working to achieve five strategic priorities, to: About Proceedings of Royal Society B

Proceedings of the Royal Society B
is the Royal Society's flagship international biological research journal, dedicated to the rapid publication and broad dissemination of high-quality research papers, reviews and comments and reply papers. Its scope is diverse and incorporates all areas of the biological sciences. It is particularly noted for ecology in the widest sense and behavioral and evolutionary biology. All papers are stringently peer-reviewed and the criteria for publication include scientific excellence, originality and interest across biological disciplines. To read the current issue of the journal, go to: http://publishing.royalsociety.org/index.cfm?page=1569.

Source: Jamie Nunnelly
National Institute of Statistical Sciences




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