Strengthening The Reporting Of Genetic Association Studies

Main Category: Genetics
Also Included In: Biology / Biochemistry;  Cancer / Oncology
Article Date: 04 Feb 2009 - 3:00 PDT

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Making sense of rapidly evolving evidence on genetic associations is crucial to making genuine advances in human genomics and the eventual integration of this information in the practice of medicine and public health. However, "assessment of the strengths and weaknesses of this evidence, and hence the ability to synthesize it, has been limited by inadequate reporting of results," says an international team of researchers in this week's PLoS Medicine.

Julian Little (University of Ottawa, Ontario, Canada) and colleagues outline their recommendations to improve such reporting-their recommendations are called the STREGA statement (STREGA stands for Strengthening the REporting of Genetic Association Studies). The statement is being published simultaneously in six other journals: Annals of Internal Medicine, European Journal of Clinical Investigation, European Journal of Epidemiology, Genetic Epidemiology, Human Genetics, and Journal of Clinical Epidemiology.

Citation:
"STrengthening the REporting of Genetic Association Studies (STREGA)-An extension of the STROBE Statement."
Little J, Higgins JPT, Ioannidis JPA, Moher D, Gagnon F, et al. (2009)
PLoS Med 6(2): e1000022. doi:10.1371/journal.pmed.1000022
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