"Structure-function Relationships In The Emerging Enzymes CTX-M"

Main Category: Infectious Diseases / Bacteria / Viruses
Article Date: 21 Mar 2009 - 3:00 PDT

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Richard Bonnet (from the Bacteriology Laboratory of the Medical School,Clermont-Ferrand), presented at March 11, in the auditory of the National Institute of Health Dr. Ricardo Jorge, the lecture "Structure-function relationships in the emerging enzymes CTX-M", in the contexte of the three conferences os March dedicated to antibiotics resistance.

The speaker underlined the actual emergence os beta-lactamases from CTX-M family and the importance of it's conformational structure in the inactivation of beta-lactamic antibiotics.

The emergence of resistance to the most commonly used antibioticsin the treatment of infections constitutes a threat not to be minimized in public health, therefore this issue is the core activity of the National Reference Laboratory of Antibiotic Resistance(LNR-RA), from the Departament of Infectious Diseases.

Besides the patient implications, bacterial resistance to antibiotics generates considerable costs in Health Systems of most of industrialized countries.

Instituto Nacional de Saúde Doutor Ricardo Jorge
http://www.insa.pt