Search is Powered by Google
Follow us on:
Follow our health news on Twitter
Follow Our News on Facebook
Personalization
login | register
Arthritis / Rheumatology News

New Tool To Accelerate Discovery Of Autoimmune Disease Mechanisms And Therapies

Main Category: Arthritis / Rheumatology
Also Included In: Irritable-Bowel Syndrome;  Multiple Sclerosis;  IT / Internet / E-mail
Article Date: 31 Oct 2009 - 0:00 PDT

email icon email to a friend   printer icon printer friendly   write icon view / write opinions


Current Article Ratings:

Patient / Public:4 stars

3.8 (10 votes)

Health Professional:not yet rated

Article Opinions: 0 posts

Currently, 5 - 8% of the U.S. population is afflicted with an autoimmune disease. Many of these are chronic and require life-long care. Moreover, different autoimmune diseases aggregate within a single family, suggesting they are caused by disruptions in common biological pathways.

To help researchers investigate these common pathways, The Jackson Laboratory has published Pathways to Discovery: Autoimmune Diseases (http://www.jax.org/jaxmice/pathways/autoimmune), a unique, interactive, and publicly accessible online resource that illustrates the genetic networks involved in five common autoimmune diseases: inflammatory bowel disease, rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis.

The backbone of the new tool is five "spider-web" diagrams that depict the gene/proteins involved in two or more of the five diseases. The symbols in the diagrams represent cytokines, transmembrane receptors, enzymes, nuclear receptors, and transcriptional regulators. The resource also provides gene- and disease-specific references, links to JAX® Mice strains (including inducible mouse models) that can be used to research the five diseases, and descriptions of JAX® In Vivo Services for compound efficacy testing.

Pathways to Discovery: Autoimmune Diseasespromises to accelerate the discovery of autoimmune disease mechanisms and therapeutic interventions for both new and existing targets.

Source: Joyce Peterson
Jackson Laboratory




Personalized Homepage Weekly Newsletters Daily News Alerts
Hemophilia Opioid Induced Constipation Pneumococcal Disease ADHD Anxiety Asthma Atrial Fibrillation Autism Cancer Diabetes Lung Cancer Lupus Medicare / Medicaid Obesity and BMI Pancreatic Cancer Stem Cells All 'What Is...' Articles

Ophthalmology Urology
About Us News Licensing Free Website Feeds Free Tools & Content Tell a Friend Accessibility Help / FAQ Article Submission Links Contact Us

add medical news today to your facebook
medical news gadget

Haiti Appeal

Haiti Appeal Image
The severe earthquake that struck Haiti has inflicted damage and devastation on a massive scale. Please donate to the Doctors Without Borders Haiti Appeal.

PLEASE DONATE HERE


These are the most read articles from this news category for the last 6 months:
Top Article Star
What Is Ibuprofen? What Is Ibuprofen Used For?
19 Aug 2009
Ibuprofen is an NSAID (non-steroidal anti-inflammatory drug) that is commonly used for the relief of symptoms of arthritis, fever, primary dysmenorrhea (menstrual pains), and as an analgesic (a medication given to reduce...


How to Build a Better Relationship with Your Doctor
How to Build a Better Relationship with Your Doctor

With appointments lasting 15 minutes or less, it can be hard to communicate with your doctor. But there are some tips on how to get the most out of your visit.

more videos are available in our health videos section.