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"Our trial is the first study to show the benefits of use of a 5α-reductase inhibitor to reduce the need for aggressive treatment in men undergoing active surveillance for low-risk prostate cancer...delaying their time to pathological progression and initiation of primary therapy."
"These data are consistent with the hypothesis that dutasteride reduces the volume of low-grade prostate cancers but has no effect, or even an adverse effect, on the progression of high-grade disease. Thus, although reducing overall prostate cancer detection, dutasteride could plausibly have no effect (or possibly a deleterious one) on prostate cancer mortality."
"The benefit of dutasteride is to reduce the amount of low-grade cancer, not to reduce the risk of being diagnosed with higher-grade cancer. This reduction leads to fewer men with biopsy-detectable prostate cancer, and therefore fewer treatment interventions. Dutasteride...provides a treatment option for men with low-risk, localized disease."
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Not to be reproduced without the permission of Medical News Today.
”Dutasteride in localised prostate cancer management: the REDEEM randomised, double-blind, placebo-controlled trial”
Prof, Dr Neil E Fleshner et al.
The Lancet, Early Online Publication, 24 January 2012, doi:10.1016/S0140-6736(11)61619-X
Visit our Prostate / Prostate Cancer category page for the latest news on this subject.
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Rattue, G. (2012, January 25). "Dutasteride Slows Down Early Stage Prostate Cancer Progression." Medical News Today. Retrieved from
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