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"This is the first concrete evidence that FC treatment does not impair quality of life over the long term. Because FC is effective at creating long term remission, free of any serious symptoms, patients reported benefits from not constantly relapsing and having to receive repeated treatment."
"The CLL4 clinical trial showed the benefits of FC for patients and is the basis for its use today, in combination with the drug rituximab, as the standard treatment of CLL. Additionally, it has helped doctors to customize treatment for each patient by establishing testing for different prognostic markers in CLL that can dictate how each individual's disease will respond to therapy."
"CLL is predominantly a disease of the elderly, so side-effects that drugs can have on patients are a major concern, with more aggressive drugs causing nausea, fatigue and susceptibility to infection. CLL remains an incurable cancer but this study offers reassurance that powerful initial treatment can allow patients to enjoy a high quality of life for years in remission."
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