Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
"Selective reporting of research results undermines the integrity of the evidence base, which ultimately deprives clinicians of accurate data for prescribing decisions."
"The magnitude of publication bias found for anti-psychotics was less than that found previously for antidepressants, possibly because anti-psychotics demonstrate superiority to placebo more consistently.
With further studies investigating publication bias in other drug classes, a more accurate evidence base can emerge. To that end, increased access to FDA reviews has been advocated. At the present time, the FDA is not as transparent with its clinical trial data as it could be.
It is encouraging that the FDA has convened a Transparency Task Force. If the agency fulfills its mission to increase transparency, the public health will surely benefit."
Copyright: Medical News Today
Not to be reproduced without the permission of Medical News Today.
“Publication Bias in Antipsychotic Trials: An Analysis of Efficacy Comparing the Published Literature to the US Food and Drug Administration Database” Turner EH, Knoepflmacher D, Shapley L (2012)
PLoS Med 9(3): e1001189. doi:10.1371/journal.pmed.1001189
Visit our Schizophrenia category page for the latest news on this subject.
Please use one of the following formats to cite this article in your essay, paper or report:
Rattue, Grace. "2nd Generation Anti-Psychotic Drugs Publication Bias." Medical News Today. MediLexicon, Intl., 22 Mar. 2012. Web.
6 Mar. 2014. <http://www.medicalnewstoday.com/articles/243196>
Rattue, G. (2012, March 22). "2nd Generation Anti-Psychotic Drugs Publication Bias." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
If you write about specific medications, operations, or procedures please do not name healthcare professionals by name.
For any corrections of factual information, or to contact our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/articles/243196.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2014 All rights reserved. MNT (logo) is the registered trade mark of MediLexicon International Limited.