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"The exome array allowed us to test a large number of individuals in this case, more than 8,000 people very efficiently. We expect that this type of analysis will be useful for finding low-frequency variants associated with many complex traits, including obesity or cancer."
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Jeroen R Huyghe, Anne U Jackson, Marie P Fogarty, Martin L Buchkovich, Alena Stančáková, Heather M Stringham, Xueling Sim, Lingyao Yang, Christian Fuchsberger, Henna Cederberg, Peter S Chines, Tanya M Teslovich, Jane M Romm, Hua Ling, Ivy McMullen, Roxann Ingersoll, Elizabeth W Pugh, Kimberly F Doheny, Benjamin M Neale, Mark J Daly, Johanna Kuusisto, Laura J Scott, Hyun Min Kang, Francis S Collins, Gonçalo R Abecasis
Nature Genetics (2012) doi:10.1038/ng.2507
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
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