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"Our main finding was that maternal use of folic acid supplements around the time of conception was associated with a lower risk of autistic disorder. This finding does not establish a causal relation between folic acid use and autistic disorder but provides a rationale for replicating the analyses in other study samples and further investigating genetic factors and other biological mechanisms that may explain the inverse association."
"It is reassuring that the study by Surén et al found no association between folic acid supplementation and an increased risk for autistic disorder or ASDs.
This should ensure that folic acid intake can continue to serve as a tool for the prevention of neural tube birth defects. The potential for a nutritional supplement to reduce the risk of autistic disorder is provocative and should be confirmed in other populations."
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JAMA (Journal of the American Medical Association) 2013;309(6):570-577
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