Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
Deep brain stimulation (DBS) is a surgical procedure that involves placing a neurostimulator in the brain which sends out electrical impulses to specific regions of the brain.
The electrical impulses are sent out to block abnormal signals that can cause a number of different neurological disorders.
The procedure is also being studied as a potential form of treatment for Tourette syndrome and major depression.
The DBS system is made up of three different components:
The lead (also called an electrode) is a thin insulated wire which is implanted in the target region of the brain.
The extension wire travels under the skin and connects the lead to the implanted pulse generator - which sends out the electrical signals.
DBS alters activity in the brain in a controlled manner, as opposed to lesioning techniques its effects are completely reversible.
DBS is associated with an increased release of adenosine triphosphate (ATP), leading to a build up of adenosine. ATP is an energy-carrying molecule found in the cells of all living things.
According to a study published in the prestigious journal Nature Medicine, adenosine A1 receptor activation depresses excitatory transmission in the thalamus thus reducing both tremor and DBS induced side effects.1
DBS is mainly carried out on patients whose symptoms cannot be properly treated with medications.
The procedure does not destroy any nerve cells or healthy brain tissue.
Even though the majority of patients will have to continue taking medication following DBS, many will experience a considerable reduction in their Parkinson's disease symptoms and and will probably be on fewer drugs.
DMS typically involves two separate surgeries:
Some people suffering from severe Parkinson's disease cannot be controlled on medications, and additional methods of alleviating symptoms, such as DBS, are necessary.Results of a two-year clinical trial found that DBS greatly improves overall quality of life and social functioning among patients in earlier stages of Parkinson's disease.2
In addition to treating Parkinson's disease, DBS can help treat the symptoms of the following conditions and problems:
DBS can potentially be used to treat:
DBS is a safe procedure, however, there is a small risk of:
Written by Joseph Nordqvist
Copyright: Medical News Today
Not to be reproduced without the permission of Medical News Today.
1. Nature Medicine - "Adenosine is crucial for deep brain stimulation–mediated attenuation of tremor"
2. Medical News Today - "Deep Brain Stimulation Effective In Early Parkinson's"
3. Medical News Today - "Deep Brain Stimulation Effective For Most Common Hereditary Dystonia"
4. Medical News Today - "Drugs For Essential Tremor Stopped By Most Patients After Deep Brain Stimulation Surgery"
5. The Lancet - "Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder"
6. Medical News Today - "Deep Brain Stimulation May Be Effective Treatment For Tourette Syndrome"
7. Medical News Today - "Outcomes Of Deep Brain Stimulation For Depression Sustained For One Year"
8. Medical News Today - "Obesity Could Be Treated With Deep Brain Stimulation"
Visit our Neurology / Neuroscience category page for the latest news on this subject.
Please use one of the following formats to cite this article in your essay, paper or report:
Nordqvist, Joseph. "What is deep brain stimulation?." Medical News Today. MediLexicon, Intl., 2 Sep. 2013. Web.
12 Dec. 2013. <http://www.medicalnewstoday.com/articles/265445>
Nordqvist, J. (2013, September 2). "What is deep brain stimulation?." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
If you write about specific medications, operations, or procedures please do not name healthcare professionals by name.
For any corrections of factual information, or to contact the our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/articles/265445.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2013 All rights reserved. MNT (logo) is the registered trade mark of MediLexicon International Limited.