Fatal Infections In Critically Ill Patients May Be Caused By Cosmetic Products

Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Infectious Diseases / Bacteria / Viruses
Article Date: 31 Jan 2008 - 2:00 PDT

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Healthy consumers can handle the low levels of bacteria occasionally found in cosmetics. But for severely ill patients these bacteria may trigger life-threatening infections, as patients in the intensive care unit at one Barcelona hospital discovered after using contaminated body moisturiser. The Burkholderia cepacia bacteria outbreak is detailed in the open access journal, Critical Care.

Five patients suffered from infection including bacteremia, lower respiratory tract infection and urinary tract infection associated with the bacterial outbreak in August 2006. Skin care products sold in the European Union are not required to be sterile, but there are limits to the amount and type of bacteria that are permitted.

The Hospital Universitari del Mar, Universitat Autònoma de Barcelona's routine infection control surveillance pinpointed the unwelcome bacteria in five patients' biological samples. Researchers tested a number of environmental samples, and discovered that moisturizing body milk used in the patients' care was a B. cepacia reservoir. Pulsed-field gel electrophoresis experiments confirmed that all of the strains of B. cepacia bacteria found in patient and environmental samples were from the same bacterial clone. Tests on sealed containers of the moisturizer confirmed that the bacteria had not invaded the product after it had been opened, but that it was contaminated during manufacturing, transportation or storage.

"This outbreak of nosocomial infection caused by B. cepacia in five severely ill patients supports a strong recommendation against the use cosmetic products for which there is no guarantee of sterilization during the manufacturing process," says study author Francisco Álvarez-Lerma.

B. cepacia is a group or "complex" of bacteria that can be found in soil and water. They have a high resistance to numerous antimicrobials and antiseptics and are characterised by the capacity to survive in a large variety of hospital microenvironments These bugs pose little medical risk to healthy people. However, those with weakened immune systems or chronic lung diseases, particularly cystic fibrosis, may be more susceptible to B. cepacia infection. B cepacia is a known cause of hospital infections.

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Article adapted by Medical News Today from original press release.
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1. Moisturizing body milk as a reservoir of Burkholderia cepacia: outbreak of nosocomial infection in a multidisciplinary intensive care unit
Francisco Alvarez-Lerma, Elena Marull, Roser Terradas, Concepcion Segura, Irene Planells, Pere Coll, Hernando Knobel and Antonia Vazquez
Critical Care (in press)

Click here for access to the published article. All articles are available free of charge, according to BioMed Central's open access policy.

2. Critical Care is a high quality, peer-reviewed, international clinical medical journal. Critical Care aims to improve the care of critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists. The journal is edited by Prof Jean-Louis Vincent (Belgium) and has an Impact Factor of 3.12

3. BioMed Central http://www.biomedcentral/) is an independent online publishing house committed to providing immediate access without charge to the peer-reviewed biological and medical research it publishes. This commitment is based on the view that open access to research is essential to the rapid and efficient communication of science.

Source: Charlotte Webber
BioMed Central