Which Is The Most Important Risk Factor For Prostate Cancer: Race, Family History, Or Baseline PSA Level?

Main Category: Prostate / Prostate Cancer
Also Included In: Urology / Nephrology;  Cancer / Oncology
Article Date: 11 Jun 2008 - 8:00 PDT

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ORLANDO, FL (UroToday.com) - Compelling data is emerging about the prognostic power of a man's baseline PSA value and in its ability to dictate risk of developing prostate cancer (CaP).

Does the baseline PSA value have the same predictive power in men who are already at a very high risk for developing CaP? Mondo and colleagues report data that certainly suggest that this is indeed the case. 329 African American patients with a positive family history of prostate cancer who enrolled in a longitudinal prostate cancer screening study were identified.

These high risk men who had a baseline PSA value below the age-adjusted median were unlikely to develop CaP despite their baseline high risk status.

Presented by Dana M Mondo, MD, Kimberly A Roehl, MD, Stacy Loeb, MD, Sara N Gashti, MD, Christopher R Griffin, MD, Norm D Smith, MD, Robert B Nadler, MD, William J Catalona, MD, at the Annual Meeting of the American Urological Association (AUA) - May 17 - 22, 2008. Orange County Convention Center - Orlando, Florida, USA.

Reported by UroToday.com Contributing Editor Alexander Kutikov, MD

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