Alzheimer's Society Comment On Nicotinamide Vitamin B3 Study In Journal Of Neuroscience

Main Category: Alzheimer's / Dementia
Also Included In: Neurology / Neuroscience
Article Date: 05 Nov 2008 - 9:00 PDT

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An over-the-counter vitamin in high doses prevented memory loss in mice with some aspects of Alzheimer's disease, according to a paper published today (5 November) in the Journal of Neuroscience.

The vitamin also strengthened scaffolding along which information travels in brain cells, helping to keep neurons alive and further preventing symptoms in mice genetically wired to develop Alzheimer's.

This new research demonstrates that Nicotinamide (vitamin B3), can help mice with some aspects of Alzheimer's disease to maintain their memory.

From the research, it appears that Nicotinamide has more than one beneficial effect on nerve cells including the facilitation of the recycling of the 'bad' phosphorylated tau. This research is interesting as it points towards new ways of treating Alzheimer's disease.

Nicotinamide occurs naturally in meat, fish, beans, cereals and potatoes and is cheap and easy to take. However, more research is now needed to explore the possible mechanisms involved so we can better understand if Nicotinamide could have the same effect in people and, if it does, what level of vitamin intake would be required.

The best evidence around reducing your risk of dementia is to eat a healthy balanced diet, take regular exercise, don't smoke and check your blood pressure and cholesterol.

Susanne Sorensen
Head of Research
Alzheimer's Society

Information about Alzheimer's Society

Alzheimer's Society is the leading care and research charity for people with all forms dementia and their carers. It provides information and education, support for carers, and quality day and home care. It funds medical and scientific research and campaigns for improved health and social services and greater public understanding of dementia.

Alzheimer's Society provides a national help line on 0845 3000 336 and website alzheimers.org.uk. Please include this information in any publication that uses these comments.

Alzheimer's Society

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