Material Nanosizing Effect On Living Organism

Main Category: Immune System / Vaccines
Also Included In: Biology / Biochemistry
Article Date: 11 Apr 2009 - 3:00 PDT

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Non-actuation of immune system except innate immunity against materials gives the nonspecific nature to their bioreaction and micro/nanosizing makes materials biointeractive with biological organism.

This leads to the characteristic phenomena of no rejection reactions to artificial organs in macro, nonspecific phagocytosis to cells and inflammation to tissue in micro, and direct invasion into the internal body in nano.

The bioreactive nature induces inflammation and leads to the conversion of functions through biological process, from biocompatibility to stimulus in Ti abraded particles and asbestos, from non-bone substitutional to bone substitutional in nanoapatite and from non-cell adhesive to cell adhesive in CNTs.

Journal of the Royal Society Interface

Journal of the Royal Society Interface is the Society's cross-disciplinary publication promoting research at the interface between the physical and life sciences. It offers rapidity, visibility and high-quality peer review and is ranked fifth in JCR's multidisciplinary category. The journal also incorporates Interface Focus , a peer-reviewed, themed supplement, each issue of which concentrates on a specific cross-disciplinary subject.

Journal of the Royal Society Interface

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