Do NSAIDs Delay Onset Of Dementia?

Main Category: Alzheimer's / Dementia
Also Included In: Neurology / Neuroscience;  Pain / Anesthetics
Article Date: 30 Apr 2009 - 4:00 PST

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New research shows that people over 65 who are heavy users of nonsteroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen and Naproxen, show a high incidence of dementia.

The researchers conclude that NSAIDs may delay, not prevent, dementia. The study by the American Academy of Neurology will be published in the Journal of Neurology. 'It is hard to draw any conclusions from this study. It found a high incidence of dementia in older people who frequently use NSAIDS. But these people also had a higher incidence of heart disease, high blood pressure and obesity, all of which increase risk of dementia.

The overall picture is mixed, but the most robust research from controlled clinical trials suggests NSAIDs do not delay, prevent or treat dementia. One million people will develop dementia in the next ten years. We desperately need to start investing more to improve treatments today and find a cure for tomorrow.'

Professor Clive Ballard
Director of Research
Alzheimer's Society

Reference:

Breitner et al, Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort. Journal of Neurology.

Alzheimer's Society

Alzheimer's Society is the leading care and research charity for people with all forms of dementia and their carers. It provides information and education, support for carers, and quality day and home care. It funds medical and scientific research and campaigns for improved health and social services and greater public understanding of dementia.

Source
Alzheimer's Society

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