The Overlap In Gastroesophageal Reflux Disorder And Irritable Bowel Syndrome
A research article published in the World Journal of Gastroenterology provides more evidence regarding the relationship between GERD and IBS. The research team led by Professor Malekzadeh and Dr.Nasseri-Moghaddam from Digestive disease research center, Shariati Hospital, Tehran University of Medical Sciences performed a retrospective study in a gastroenterology clinic setting to investigate the prevalence of GERD in patients with a primary diagnosis of IBS and vice versa. They also measured the prevalence of other functional symptoms of the gastrointestinal tract in patients with GERD, IBS or both. They recruited 6 476 patients presenting to the GI clinic with symptoms of functional dysfunction of the GI tract.
This data is from a very large number of patients, probably the largest data set that has been reported about the overlap between IBS and GERD in the literature. It also shows that not only is GERD more common among patients with IBS, or IBS is more common in patients with GERD, but also other functional symptoms such as nausea and changes in bowel movement or even extra gastrointestinal symptoms such as headache are more prevalent in patients who present with overlapping GERD and IBS. This is more evidence that some systemic component underlies the pathophysiology of both of these disorders; the more severe the disorder the more the chance of having multiple symptoms and suffering from both GERD and IBS.
Yarandi SS, Nasseri-Moghaddam S, Mostajabi P, Malekzadeh R. Overlapping gastroesophageal reflux disease and irritable bowel syndrome: Increased dysfunctional symptoms. World J Gastroenterol 2010; 16(10): 1232-1238
World Journal of Gastroenterology
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