Doctor Warns Against St. John's Wort For Anxiety
Main Category: Anxiety / StressAlso Included In: Complementary Medicine / Alternative Medicine
Article Date: 07 Apr 2010 - 2:00 PDT
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2.18 (11 votes) |
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In a broad-based review of studies focused on drugs that treat anxiety, a Saint Louis University doctor found no evidence supporting the use of so-called "natural" treatments in combating the effects of anxiety.
St. John's wort, kava extract and valerian, herbal remedies touted on the Internet, have not been proven to be effective in treating anxiety wrote Kimberly Zoberi, M.D., associate professor of family and community medicine at Saint Louis University School of Medicine. Additionally, she raised concerns about the safety of valerian, particularly lacking any long-term studies of the herb.
"Patients should be extremely cautious about garnering medical advice from the Internet," says Zoberi. "There is no evidence that those medications are effective. If a patient wishes to avoid drug therapy, her doctor can suggest alternatives such as cognitive behavioral therapy."
In addition to the findings regarding "natural" treatments, Zoberi compared the differing prescription drug regimens available on the market for patients suffering from anxiety. According to Zoberi, most physicians recommend selective serotonin reuptake inhibitors (SSRIs) as a first-line treatment because they were safe, effective and less expensive. However, some patients suffer sexual or gastrointestinal side effects.
Zoberi found that medications from the anticonvulsant class of drugs are among the quickest and most effective ways to provide relief to patients in distress without the side effects of other first-line treatments. The downside is that these prescriptions are fairly expensive compared to other treatments.
Ultimately, Zoberi strongly recommends consulting with a health care professional before beginning any drug regimen for anxiety.
The review article was published in last month's issue of the Journal of Family Practice.
Established in 1836, Saint Louis University School of Medicine has the distinction of awarding the first medical degree west of the Mississippi River. The school educates physicians and biomedical scientists, conducts medical research, and provides health care on a local, national and international level. Research at the school seeks new cures and treatments in five key areas: cancer, infectious disease, liver disease, aging and brain disease and heart/lung disease.
Source: Saint Louis University Medical Center
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Visitor Opinions In Chronological Order (5)
St. John's Wort Not Suitable For Anxiety
posted by Nancy Winlove-Smith on 13 Apr 2010 at 6:02 pmAs a Professional Member of the Ontario Herbalist Association, I would not personally recommend St. John's Wort for anxiety. The botanical that should have been studied was Valeriana officials.
Not Entirely True...St John Wort..Kava
posted by Anon on 3 May 2010 at 10:10 amThere is a body of literature that shows that StJWort may be helpful for mild to moderate depression, and given the overlap and diagnostic confusion between 'agitated' depression and anxiety, it is probable that StJWort may have some optimal benefit for 'anxiety'. If StJWort works according to the MAO hypothesis, then a similar mechanism that provides anxiolytic relief via antidepressants should work here. Interaction effects via CP450 are the main concern with StJWort.
There is some evidence to suggest that kava is helpful for anxiety. I think the primary issue is safety (which some have found to be exaggerated, while other researchers remain concerned). One study found it as effective as low dose buspirone, another as effective as oxazepam. The quality of the product is probably the biggest confound in these studie
Really?
posted by Alex Kotlar on 28 Sep 2010 at 9:25 pmI wonder how much Zoberi was paid, because I can't imagine he was stupid enough to put his name behind this kind of "research" announcement. Anti-convulsants have the worst cognitive profiles besides anti-psychotics, are known to irreparably damage cognition, cause low bone density, immune dysfunction (read up on what sodium channel blockers do), are generally arrhythmogenic, and for some patients use results in multi-organ failure, sudden heart failure, aseptic meningitis, and a litany of other nasty side effects at clinically significant rates.
On the other hand, St. John's Wort has plenty of clinical evidence behind it, mostly in Europe, known gene & neurotransmitter effects (comparable to imipramine), and a fantastic safety record.
Messages to the public like these are the reason the United States needs a revolution in the medical industry. The result should be something that can no longer be considered an amalgam of corporate greed. Regardless of your position on the current state of affairs, it is in your best interest to visit pubmed.com and do your own research regarding true benefit effect size and side effect frequency.
disagree
posted by Kathy on 10 Feb 2011 at 12:10 pmDon't know what "research" this doctor is refering to, but from personal experience. St John's wort was helpful. The SSRI Effexor actually caused anxiety for me. Just Sayin'
Depression
posted by kathryn on 13 Feb 2011 at 7:45 amI have found brewers yeast a great recipe for depression.St johns wort for some reason raised my eye pressure and gave them a glazed look.
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