Genetic Test Helps Predict Cellulite - Before The Swimsuit Makes You Look Fat

Main Category: Genetics
Also Included In: Dermatology
Article Date: 10 Jun 2010 - 12:00 PDT

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As summer swimsuit season heats up, women around the world will inspect their looks in the mirror. A majority of them will see cellulite - at some point - but a new genetic test may be able to help them avoid cellulite before anyone notices.

Molecular dermatology research and development innovator DermaGenoma, Inc. just released the CelluliteDX Genetic Test for Moderate to Severe Cellulite (gynoid lipodystrophy). The $249 test helps doctors predict if a patient is at a high risk for developing Nurnberger-Muller grade 2 (or greater) cellulite. The information allows doctors to develop a plan which may include therapy and/or lifestyle changes that may reduce the risk of developing moderate to severe cellulite.

Existing therapies are unlikely to reverse severe cellulite once it has occurred. Early lifestyle changes including exercise, medication choices (i.e. avoiding birth control and hormone replacement therapy), and therapies, such as laser therapy, may slow or stop development of severe cellulite and improve visual aesthetics.

"Even though cellulite affects a large percentage of women, very few scientific studies have attempted to understand the underlying molecular and physiological basis. Our study of cellulite is a breakthrough in the understanding of the cause of cellulite, and ushers an era of new potential therapies for cellulite," says Enzo Emanuele, MD, Research fellow, at the University of Pavia, Italy.

CelluliteDX reports the presence or absence of a specific variation in the angiotensin I-converting enzyme (ACE) gene, which has an important role in the cardiovascular system.

"The CelluliteDX test is most appropriate for women who have not yet developed moderate to severe cellulite and may have a family history of cellulite," says DermaGenoma CEO Andy Goren.

A patient testing positive for the ACE variant has approximately a 70% chance of developing moderate to severe cellulite.

The patent-pending CelluliteDX Genetic Test kit is available through qualified doctors, who collect a genetic sample using a cheek swab. The sample is mailed to DermaGenoma's CLIA-certified laboratory for analysis. Results are strictly confidential, delivered only to doctors in two to three weeks.

Source
DermaGenoma, Inc.

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