Proper Storage of Epinephrine for Anaphylaxis

Main Category: Ear, Nose and Throat
Article Date: 20 Mar 2005 - 7:00 PDT

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Epinephrine in prefilled syringes may not be stable at certain temperatures and humidity, according to a study presented today at the 2005 AAAAI Annual Meeting in San Antonio.

Epinephrine is the drug of choice in the first aid treatment of anaphylaxis. Keith Simons, PhD, University of Manitoba, Winnipeg, MB, Canada and colleagues took syringes containing a 0.3 mg dose of epinephrine and stored them at the same temperature with different humidity and light conditions for 5 months.

The findings of the study showed that storage of the syringes at low temperature plus low humidity appeared to compromise stability more than high temperature plus high humidity. They also noted that the syringes retained a 0.3 mg epinephrine dose for only 2 months in a hot, dry environment.

American Academy of Allergy, Asthma & Immunology (AAAAI)
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Milwaukee, WI 53202
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