Nuvilex Anticipates Enhancement Of Multi-Drug Cancer Therapies By Inclusion Of Encapsulated Cells

Main Category: Cancer / Oncology
Also Included In: Pancreatic Cancer
Article Date: 17 Jun 2011 - 9:00 PDT


Nuvilex, Inc. (OTCQB: NVLX) described today potential advantages of cell encapsulation technology for use in cancer therapies when more than one cancer-fighting drug is used. The cell encapsulation technology platform forms the basis for Nuvilex's recently acquired pancreatic cancer treatment.

Currently, many cancer chemotherapy regimens under investigation and some currently in use, rely on multiple drugs given simultaneously or in sequence (combination chemotherapy). The effectiveness of combination chemotherapy regimens may also be improved from the use of encapsulated cell technology. As previously shown in clinical trials, the inclusion of encapsulated cells allows for the use of lower drug doses for a single drug. Nuvilex is now interested in expanding cancer therapy capability to include encapsulated cells when more than one cancer-fighting agent is used.

The benefits of using the cell encapsulation technology together with a single cancer drug were clearly demonstrated in pancreatic cancer clinical trials. A major breakthrough occurred when the encapsulated cells enabled the use of lower cancer-fighting drug doses. This resulted in fewer side effects than normally occur. Most importantly, the effectiveness of the cancer-fighting drug was enhanced when used in combination with encapsulated cells, leading to improved clinical outcomes and quality of life.

Since then, improvements in cancer treatment have been demonstrated in two animal models when the cell encapsulation technology was combined with two cancer-fighting drugs. In those studies, the two drugs were both converted by the encapsulated cells increasing the overall therapeutic effect.

In commenting on the advantages of using cell encapsulation technology in combination with multiple cancer-fighting drugs, Nuvilex's President and CEO, Dr. Robert F. Ryan, stated: "The first combination chemotherapeutic regimens to fight cancer were successfully introduced in the 1960's and are now used on a regular basis. The advantages of using cell encapsulation with combination chemotherapy regimens are of great interest to us. Together, Nuvilex and SG Austria have initiated further improvements and already put them into development. We believe inclusion of encapsulated cell technology in combination chemotherapy treatments will improve the therapeutic results and increase patients' overall quality of life as a result."

Source:
Nuvilex, Inc.

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