Negative Emotions Influence Brain Activity During Anticipation And Experience Of Pain
"Patients who have high expectations of pain may have a harder time coping with the actual source of pain, as is often seen in patients with irritable bowel syndrome," said Steven J. Coen, PhD, of the Wingate Institute of Neurogastroenterology and lead author of this study.
Researchers of this study observed higher levels of neuroticism associated with brain activity during anticipation of pain in regions of the brain responsible for emotional and cognitive pain processing. During pain, however, activity in these regions was reduced. This behavior may help explain the greater incidence of those with higher neuroticism attending outpatient pain clinics and being at greater risk for developing chronic pain conditions.
"Previous research has shown that there is a connection between a patient's emotions and their perceived levels of pain, especially in gastrointestinal disorders," explained Dr. Coen. "Our study shows a patient's state of mind should be noted by their physician and taken into account when determining treatment regimens - both behavioral and pharmacologic."
For more information on IBS, please read the AGA brochure "Understanding Irritable Bowel Syndrome" at http://www.gastro.org/patient-center/digestive-conditions/irritable-bowel-syndrome.
American Gastroenterological Association
Source: EurekAlert!, the online, global news service operated by AAAS, the science society
Please use one of the following formats to cite this article in your essay, paper or report:
American Gastroenterological Association. "Negative Emotions Influence Brain Activity During Anticipation And Experience Of Pain." Medical News Today. MediLexicon, Intl., 21 Sep. 2011. Web.
25 Apr. 2017. <http://www.medicalnewstoday.com/releases/234689.php>
American Gastroenterological Association. (2011, September 21). "Negative Emotions Influence Brain Activity During Anticipation And Experience Of Pain." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
Contact our news editors
For any corrections of factual information, or to contact our editorial team, please see our contact page.
Copyright Medical News Today: Excluding email/sharing services explicitly offered on this website, material published on Medical News Today may not be reproduced, or distributed without the prior written permission of Medilexicon International Ltd. Please contact us for further details.