Commonly Prescribed Glaucoma Drug May Be Effective In Treating Male Pattern Baldness And Other Forms Of Alopecia
"We hope this study will lead to the development of a new therapy for balding which should improve the quality of life for many people with hair loss," said Valerie Randall, a researcher involved in the work from the University of Bradford, Bradford, UK. "Further research should increase our understanding of how hair follicles work and thereby allow new therapeutic approaches for many hair growth disorders."
To make this discovery, Randall and colleagues conducted three sets of experiments. Two involved human cells and the other involved mice. The tests on human cells involved using hair follicles growing in organ culture as well as those take directly from the human scalp. In both of these experiments, the scientists found that bimatoprost led to hair growth. The third set of experiments involved applying bimatoprost to the skin of bald spots on mice. As was the case with human cells, the drug caused hair to regrow.
"This discovery could be the long-awaited follow up to Viagra that middle-aged men have been waiting for," said Gerald Weissmann, MD, editor-in-chief of The FASEB Journal. "Given that the drug is already approved for human use and its safety profile is generally understood, this looks like a promising discovery that has been right in front of our eyes the whole time. On to the front of our scalp!"
Details: Karzan G. Khidhir, David F. Woodward, Nilofer P. Farjo, Bessam K. Farjo, Elaine S. Tang, Jenny W. Wang, Steven M. Picksley, and Valerie A. Randall. The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias FASEB J doi:10.1096/fj.12-218156; http://www.fasebj.org/content/early/2012/10/25/fj.12-218156.abstract
Federation of American Societies for Experimental Biology
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