The targets for what's considered a "healthy" cholesterol level are getting lower and lower, and ads touting the benefits of cholesterol-lowering statin drugs are commonplace. So it's no surprise that many women who don't have heart disease wonder if they should start taking a statin for prevention. On the other hand, those who have watched the ups and downs of hormone therapy may feel a sense of d?j? vu about the enthusiasm for these relatively new drugs. The June issue of the Harvard Women's Health Watch says that whether you should take a statin to prevent heart disease depends upon one thing-your risk of heart attack.

If your risk is low, taking a statin or any cholesterol-lowering drug could do more harm than good. Statins can cause liver and muscle damage, and they require close monitoring. If you're trying to avoid a first heart attack, chances are good that some lifestyle choices-not smoking, controlling your weight, eating a heart-healthy diet, and getting regular exercise-may do the trick.

But for women who already have heart disease or are at very high risk for it, taking a statin, which helps lower LDL (?bad?) cholesterol, is probably a good idea-in addition to lifestyle measures. ?Everyone agrees that women with heart disease or a heart disease equivalent such as diabetes benefit-possibly even more than men-from LDL lowering,? says Dr. Paula Johnson, a member of the Harvard Women's Health Watch advisory board.

The article also tells you how to determine your heart attack risk and when to consider taking a statin.

Also in this issue:
-- A monthly osteoporosis drug
-- Pelvic organ prolapse
-- More about stevia, the herbal sweetener
-- Managing problems with macular degeneration
-- A doctor answers: How to avoid gout-aggravating foods? Why am I getting yeast infections?

Harvard Women's Health Watch is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $24 per year. Subscribe at health.harvard.edu/womens or by calling 1-877-649-9457 (toll free).

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