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A large randomized clinical trial sponsored by the National Institutes of Health is currently open at U-M and other sites across the country to address this question. Patients whose tumors are not considered HER2-positive by classic testing should not receive Herceptin outside of this trial. For information about the trial, call the U-M Cancer AnswerLine at 800-865-1125.
Additional authors: Suthinee Ithimakin, Kathleen C. Day, Fayaz Malik, Qin Zen, Scott J. Dawsey, Tom F. Bersano-Begey, Ahmed A. Quraishi, Kathleen Woods Ignatoski, Stephanie Daignault, April Davis, Christopher L. Hall, Nallasivam Palanisamy, Amber N. Heath, Nader Tawakkol, Tahra K. Luther, Shawn G. Clouthier, Whitney A. Chadwick, Mark L. Day, Celina G. Kleer, Dafydd G. Thomas, Daniel F. Hayes
Funding: National Cancer Institute grants CA129765 and CA101860; Breast Cancer Research Foundation; Komen for the Cure; Taubman Institute at the University of Michigan; Fashion Footwear Charitable Foundation of New York/QVC Presents Shoes-On-Sale; Stand Up to Cancer grant SU2C-AACR DT0409
Disclosure: Max Wicha has financial holdings in OncoMed Pharmaceuticals, receives support from Dompe and MedImmune and serves on the scientific advisory board of Veristem; Hasan Korkaya receives research support from MedImmune; Daniel Hayes has received research support from Pfizer, Novartis and Veridex and holds stock options for his role on the scientific advisory board for OncImmune.
Reference: Cancer Research, published online Feb. 26, 2013
University of Michigan Health System
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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20 Apr. 2014. <http://www.medicalnewstoday.com/releases/256927>
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