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This study was conducted by a team of researchers from the University of Utah, the University of Notre Dame, Navigen, and the ARUP Institute for Clinical and Experimental Pathology. University of Utah graduate student Jae Hyuk Yoo, co-first author on the study, was instrumental in study design and execution. Co-author Kenneth F. Grossmann, M.D., Ph.D., University of Utah assistant professor of internal medicine, also is an investigator with the University's Huntsman Cancer Institute.
Ongoing collaboration between the University of Utah and Navigen will focus on developing a more detailed understanding of the ARF6 signaling pathway and testing new compounds to prevent metastasis in pre-clinical models of melanoma and other cancers.
Dean Y. Li, M.D., Ph.D., vice dean for research and chief scientific officer at University of Utah Health Care, H.A. and Edna Benning Endowed Professor of Internal Medicine, and director of the Molecular Medicine M.D./Ph.D. programs, is senior author on the study. Li also is an investigator with the Huntsman Cancer Institute.
This study was partially funded by a grant from the Huntsman Cancer Foundation.
University of Utah Health Sciences
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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