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Rockswold SB, Rockswold GL, Zaun DA, Liu J. A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury. Clinical article. Journal of Neurosurgery, published online, ahead of print, March 19, 2013; DOI: 10.3171/2013.2.JNS121468.
Disclosure: This study was registered with the ClinicalTrials.gov database, and its registration number is NCT00170352. The work was supported by the National Institute of Neurological Disorders and Stroke Hyperbaric and Normobaric Oxygen in Severe Brain Injury Grant No. R01-NS042126-03S1. Integra LifeSciences provided technical assistance and supplies related to brain tissue O2 monitoring.
Journal of Neurosurgery Publishing Group
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