No Rebirth For Insulin Secreting Pancreatic Beta Cells
In this issue of the Journal of Clinical Investigation, George Gittes and colleagues at the Children's Hospital of Pittsburgh used a fluorescent cell labeling method in mice to determine exactly when precursor cells develop into pancreatic beta cells. They observed neogenesis during embryonic development, but did not find any evidence of neogenesis in adult mice. These data demonstrate that beta cell neogenesis is not possible in adult mice.
In a companion commentary, Michael German at the University of California, San Francisco, discusses the experiments that will be required to determine if these findings also apply to humans.
TITLE: No evidence for beta cell neogenesis in murine adult pancreas
View this article at: http://www.jci.org/articles/view/66323?key=4eb6fcd0887f4265673b
ACCOMPANYING COMMENTARY TITLE: Anonymous Sources: Where Do Adult β-Cells Come From?
View this article at: http://www.jci.org/articles/view/69297?key=6b064d7e97fbf4fa75a8
Source: EurekAlert!, the online, global news service operated by AAAS, the science society
Please use one of the following formats to cite this article in your essay, paper or report:
Journal of Clinical Investigation. "No Rebirth For Insulin Secreting Pancreatic Beta Cells." Medical News Today. MediLexicon, Intl., 26 Apr. 2013. Web.
31 Jul. 2016. <http://www.medicalnewstoday.com/releases/259609.php>
Journal of Clinical Investigation. (2013, April 26). "No Rebirth For Insulin Secreting Pancreatic Beta Cells." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
Contact our news editors
For any corrections of factual information, or to contact our editorial team, please see our contact page.
Copyright Medical News Today: Excluding email/sharing services explicitly offered on this website, material published on Medical News Today may not be reproduced, or distributed without the prior written permission of Medilexicon International Ltd. Please contact us for further details.