Reduced Daily Dose Of Lifesaving HIV Treatment Is Safe And Effective
The researchers have found a lower daily dose of an important HIV drug therapy is safe and as effective in suppressing the virus as the standard recommended dose.
The findings have been presented at the International AIDS Society Conference in Kuala Lumpur, Malaysia.
"This has the potential to affect the treatment of millions of HIV positive people," says UNSW Professor Sean Emery, the protocol chairperson of the study, known as ENCORE1 and Head of the Therapeutic and Vaccine Research Program at the Kirby Institute.
"A reduced daily dose should translate into a lower cost of treatment and permit more effective and efficient use of health care resources. Essentially, more people could receive this life-saving treatment for the same amount of funding."
HIV-positive people from 13 countries in Africa, Asia, Australia, Europe and Latin America took part in the trial. Half these people took two-thirds of the current standard daily dose of the antiretroviral (ART) efavirenz, a commonly used treatment for HIV; the other half took the standard daily dose. The 630 participants were observed regularly for a year. The results indicate that a reduction in daily dose of one third is both safe and effective compared to the higher dose currently recommended for people with HIV infection.
The research was part of a program funded with a grant of US$12.42 million from the Bill & Melinda Gates Foundation.
University of New South Wales
Source: EurekAlert!, the online, global news service operated by AAAS, the science society
Please use one of the following formats to cite this article in your essay, paper or report:
University of New South Wales. "Reduced Daily Dose Of Lifesaving HIV Treatment Is Safe And Effective." Medical News Today. MediLexicon, Intl., 7 Jul. 2013. Web.
26 Jul. 2016. <http://www.medicalnewstoday.com/releases/262916.php>
University of New South Wales. (2013, July 7). "Reduced Daily Dose Of Lifesaving HIV Treatment Is Safe And Effective." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
Contact our news editors
For any corrections of factual information, or to contact our editorial team, please see our contact page.
Copyright Medical News Today: Excluding email/sharing services explicitly offered on this website, material published on Medical News Today may not be reproduced, or distributed without the prior written permission of Medilexicon International Ltd. Please contact us for further details.