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The latest episode in the American Chemical Society's (ACS') award-winning Global Challenges/Chemistry Solutions podcast series* describes the development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells.
Based on a report by Nathan Luedtke, Ph.D., in the journal ACS Chemical Biology, the new podcast is available without charge at iTunes** and from http://www.acs.org/globalchallenges.***
Luedtke explains that the spread of melanoma and other forms of cancer beyond the original location -- a process called metastasis -- makes cancer such a serious disease. Photodynamic therapy (PDT), which involves administering a drug that kills cancer cells when exposed to light, already is available. But PDT works only on the main tumor and has other drawbacks. Luedtke's team set out to find an improved approach to PDT.
He describes successful tests in laboratory mice of one compound they synthesized. It not only killed melanoma cells, but also stopped them from metastasizing. The compound "provides the first example of a preclinical candidate possessing both of these properties," he states.
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our Melanoma / Skin Cancer category page for the latest news on this subject.
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American Chemical Society. "A one-two punch against cancer: American Chemical Society podcast." Medical News Today. MediLexicon, Intl., 7 Oct. 2013. Web.
4 Dec. 2013. <http://www.medicalnewstoday.com/releases/267013>
American Chemical Society. (2013, October 7). "A one-two punch against cancer: American Chemical Society podcast." Medical News Today. Retrieved from
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