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Do the benefits of treating depressed pregnant women with antidepressants outweigh the risks of the drug exposure to their babies in terms of neonatal health and long-term development?
That hotly debated question from scientific and ethical perspectives will be at the center of Northwestern Medicine®'s 2013 Perinatal Mental Health Meeting Nov. 6 to 8 in Chicago. National experts from various fields will present new research findings on perinatal depression as well as offer workshops in how to best treat it with psychotherapy. They also hope to launch perinatal depression as a new separate clinical discipline.
Perinatal mental health is an evolving new field of research about a huge public health problem: 10 to 14 percent of young women have depression during the perinatal period and one out of 12 pregnant women will be treated with antidepressants.
A novel event at the meeting will be a demonstration by masters-level clinicians and an actress showing new evidence-based behavioral psychotherapy techniques. Women with the disorder have altered emotional responses compared to major depression and require a different therapeutic approach. The actress will portray the true story of an actual patient who suffered from perinatal depression.
"What's the optimal treatment for pregnant women with depression to improve outcomes for their infants?" asked Northwestern Medicine psychiatrist Katherine L. Wisner, M.D., the director of the conference. "Does the benefit of treating women for depression with medication outweigh the risk to the baby? That's the critical question we have not yet answered."
Wisner, a leading scientist in perinatal depression, said a goal of the meeting is to move closer to a conclusion. Clinicians also are trying to develop a specialty of perinatal psychiatry or perinatal mental health professionals, as exists in the United Kingdom and Australia, Wisner said.
Wisner is director of Northwestern's Asher Center for the Study and Treatment of Depressive Disorders and the Norman and Helen Asher Professor of Psychiatry and Behavioral Sciences and obstetrics and gynecology at Northwestern University Feinberg School of Medicine. She's also a physician at Northwestern Memorial Hospital.
"We must remember the illnesses we see can be fatal," Wisner said. Uncontrolled depression can result in low birth weight, preterm birth, suicide, loss of interpersonal relationships, divorce and loss of a job. Conversely, the risks of antidepressants on the fetus can include preterm birth, restlessness and newborn rigidity and tremor.
Wisner talked about several pregnant patients who committed suicide after they stopped taking their medications either on their own or with the knowledge of their physicians.
The meeting, funded in part by the National Institutes of Health, will include the following topics:
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our Depression category page for the latest news on this subject.
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Northwestern University. "Antidepressants during pregnancy: what's best for mom and baby?." Medical News Today. MediLexicon, Intl., 17 Oct. 2013. Web.
18 Apr. 2014. <http://www.medicalnewstoday.com/releases/267489>
Northwestern University. (2013, October 17). "Antidepressants during pregnancy: what's best for mom and baby?." Medical News Today. Retrieved from
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