Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
This important scientific breakthrough, developed by the University of Granada, will aid the immediate use of artificially-grown skin for major burn patients, since the skin could be stored in tissue banks and made available when needed.
One of the problems major burn victims have is that, using the current protocols for artificial skin, they need to wait various weeks in order for it to be grown, using healthy skin from the own patient.
Spanish scientists, from the Tissue Engineering Research Group, from the Dept. of Histology at the University of Granada, have managed, for the first time, to grow artificial skin from stem cells of umbilical cord. Their study, published in the prestigious journal Stem Cells Translational Medicine, shows the ability of Wharton jelly mesenschymal stem cells to turn to oral-mucosa or skin-regeneration epithelia.
To grow the artificial skin, the researchers have used, in addition this new type of epithelia covering, a biomaterial made of fibrin and agarose, already designed and developed by the University of Granada research team. The work has been carried out in the laboratories of the Faculty of Medicine, alongside the Experimental Unit of the Granada "Virgen de las Nieves" University Hospital Complex.
Prior studies from this same research team, which received recognition in the World Congress on Tissue Engineering, held a few months ago in Seoul (S. Korea), already pointed to the possibility that Wharton stem cells could be turned into epithelia cells. This current work is the confirmation of those initial studies and its application to two regeneration structures: skin and oral mucosa, increasingly needed in injuries in these parts of the body.
One of the problems major-burn victims currently have is that, in order to apply the current techniques of artificial skin, a number of weeks are needed. That is because the skin needs to be grown from parts of the patient's healthy sin. "Creating this new type of skin using stem cells, which can be stored in tissue banks, means that it can be used instantly when injuries are caused, and which would bring the application of artificial skin forward many weeks", as explained by Antonio Campos, Professor of Histology at the University of Granada and one of the authors of this study.
To carry out this research, in addition to the researchers from the Dept. of Histology at the University of Granada (Ingrid Garzón, Miguel González Andrades, Mª Carmen Sánchez Quevedo, Miguel Alaminos and Antonio Campos), researchers from the Dept. of Cellular Biology at the University of Granada (Ramón Carmona), from the University of Valencia (Carmen Carda) and from the University of Florianopolis, Brazil (Juliano Miyake) have also been involved.
Wharton's jelly stem cells: a novel cell source for oral mucosa and skin epithelia regeneration. Garzón I, Miyake J, González-Andrades M, Carmona R, Carda C, Sánchez-Quevedo Mdel C, Campos A, Alaminos M. Stem Cells Transl Med. 2013 Aug;2(8):625-32. doi: 10.5966/sctm.2012-0157. Epub 2013 Jul 1.
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our Dermatology category page for the latest news on this subject.
Please use one of the following formats to cite this article in your essay, paper or report:
University of Granada. "Artificial skin grown using stem cells from the umbilical cord." Medical News Today. MediLexicon, Intl., 26 Nov. 2013. Web.
17 Apr. 2014. <http://www.medicalnewstoday.com/releases/269289>
University of Granada. (2013, November 26). "Artificial skin grown using stem cells from the umbilical cord." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
If you write about specific medications, operations, or procedures please do not name healthcare professionals by name.
For any corrections of factual information, or to contact our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/releases/269289.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2014 All rights reserved. MNT (logo) is the registered trade mark of MediLexicon International Limited.