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A manuscript in this week's issue of Blood provides important new details on potential therapeutic strategies for primary T-cell lymphoma of the gastrointestinal (GI) tract, a rare yet very aggressive disease.
In the manuscript Perry and colleagues describe 10 cases of indolent T-cell lymphoproliferative disease of the gut, associated with GI symptoms and occurring throughout the GI tract, of which all were clonal diseases as determined by gamma-chain rearrangement studies. While the course was benign with little response to therapy, investigators report 90 percent survival, calling attention to a new entity that should be recognized to avoid unnecessary aggressive therapy.
Indolent T-cell lymphoproliferative disease of the gastrointestinal tract, Authors: Anamarija M. Perry, Roger A. Warnke, Qinglong Hu, Philippe Gaulard, Christiane Copie-Bergman, Serhan Alkan, Huan-You Wang, Jason X. Cheng, Chris M. Bacon, Jan Delabie, Erik Ranheim, Can Kucuk, XiaoZhou Hu, Dennis D. Weisenburger, Elaine S. Jaffe, and Wing C. Chan, Blood - doi: 10.1182/blood-2013-07-512830
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our Lymphoma / Leukemia / Myeloma category page for the latest news on this subject.
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24 Apr. 2014. <http://www.medicalnewstoday.com/releases/269305>
Blood. (2013, November 26). "Indolent T-cell lymphoproliferative disease of the gastrointestinal tract." Medical News Today. Retrieved from
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