If there is something that we all know about in the 21st century it is stress, whether it's the stress of work, financial stress or the stress of getting the next grant funded; we are all familiar with that heart-pounding, race-against-time feeling. But this is a very modern perspective on stress. As far as physiologists are concerned, stress is a well-known factor that has driven evolution and moulded the planet's ecosystems since life began. 'Stress is a hot topic', says Shireen Davies, from the University of Glasgow, UK, one of the editors of this collection of reviews, adding that the relevance of stress at a strategic level is becoming more apparent, with global concerns about climate change and food security high on the political agenda. Explaining that responses to stress can be studied at almost every biological level, from the molecular mechanisms of cellular stress responses to stress in entire populations, Davies explains that she defines stress as the loss of homeostasis - an organism's ability to maintain a stable internal environment.

Given the pressing nature of the environmental changes that we are currently experiencing and the ubiquitous nature of stress, Davies joined with two of The Journal of Experimental Biology's Editors, Julian Dow from the University of Glasgow, UK, and Ken Lukowiak from the University of Calgary, Canada, to collate one of the most comprehensive collections of reviews dedicated to the topic to date, which is published in The Journal of Experimental Biology.

Bringing together specialists from disparate fields, Davies, Dow and Lukowiak present reviews covering stress in organisms ranging from yeast and plants to fish, birds and mammals, encompassing the molecular mechanisms that drive cellular responses to stress through to the epigenetic factors that regulate stress responses across generations. The collection features the following review papers:

Molecular basis of chill resistance adaptations in poikilothermic animals, by S.A. L. Hayward et al.

Acclimation and thermal tolerance in Antarctic marine ectotherms, by L. S, Peck et al.

What is environmental stress? Insights from fish living in a variable environment, by P. M. Schulte

Mosaic physiology from developmental noise: within-organism physiological diversity as an alternative to phenotypic plasticity and phenotypic flexibility, by H.A. Woods,

What can an ecophysiological approach tell us about the physiological responses of marine invertebrates to hypoxia? by J.I. Spicer

Organismal stress, telomeres and life histories, by P. Monaghan

The role of gibberellin signalling in plant responses to abiotic stress, byE.H.Colebrook et al.

Environmentally relevant stressors alter memory formation in the pond snail Lymnaea, by K. Lukowiak et al.

Surviving in a frozen desert: environmental stress physiology of terrestrial Antarctic arthropods, by N.M. Teets and D.L. Denlinger

Neurobiological disease etiology and inheritance: an epigenetic perspective, by B.J. Saab,and I.M. Mansuy

Neuromodulators, stress and plasticity: a role for endocannabinoid signalling, by L. Senst and J.Bains

Promoting longevity by maintaining metabolic and proliferative homeostasis, by L. Wang, et al.

Cell signalling mechanisms for insect stress tolerance, by S. A. Davies et al.

Transcellular chaperone signaling: an organismal strategy for integrated cell stress responses, by P. van Oosten-Hawle and R.I. Morimoto

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease, By V. Jovaisaite et al.

Stress adaptation in a pathogenic fungus, by A.J. P. Brown et al.