Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
A high-fiber diet reduces the severity of allergic airway disease, including decreased lung inflammation, in mice according to a study published online in Nature Medicine. These findings highlight how diet can influence immune cell development and disease outside of the gut.
Over recent decades, the incidence of allergic asthma has increased in developing countries, while the consumption of dietary fiber has decreased in these countries. Although dietary fiber intake can improve gastrointestinal disorders, it remains unclear whether it influences inflammation outside of the gut.
Benjamin Marsland and his colleagues report that mice fed a low-fiber diet develop worse lung inflammation in response to allergen challenge whereas those fed a high-fiber diet enriched with pectin have reduced allergic airway disease. The authors find that dietary fiber alters the composition of bacteria in the gut. Once ingested, these bacteria process the fiber and release metabolites, called short-chain fatty acids, which enter the blood circulation and influence the development of immune cells elsewhere in the body, including those entering the lung. In mice, administration of propionate, a short-chain fatty acid produced when gut bacteria metabolizes fiber, without increasing dietary fiber also reduced allergic inflammation in the lung and elicited the same protective effect as the pectin-rich diet.
Article adapted by Medical News Today from original press release. Source:
Please use one of the following formats to cite this article in your essay, paper or report:
Medicine, Nature. "Dietary fiber reduces asthma." Medical News Today. MediLexicon, Intl., 6 Jan. 2014. Web.
11 Mar. 2014. <http://www.medicalnewstoday.com/releases/270755>
Medicine, N. (2014, January 6). "Dietary fiber reduces asthma." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
If you write about specific medications, operations, or procedures please do not name healthcare professionals by name.
For any corrections of factual information, or to contact our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/releases/270755.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2014 All rights reserved. MNT (logo) is the registered trade mark of MediLexicon International Limited.