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Results of a clinical study utilizing the Eeva™ Technology by Auxogyn, that showed similar pregnancy rates among patients when embryos were transferred on Day 3 utilizing Eeva information versus Day 5 blastocyst transfers relying on morphology alone, were presented at the Association of Clinical Embryologists (ACE) 2014 Conference by Chris Adam, Laboratory Manager of the Glasgow Centre for Reproductive Medicine (GCRM Ltd).
"We are very pleased with the data being presented today at ACE," said Professor Fleming, Scientific Director of GCRM Ltd. "This further demonstrates how IVF clinicians and their patients can benefit from the early information that Eeva provides to assist in embryo selection."
Lissa Goldenstein, President and CEO of Auxogyn stated, "This data, combined with the launch of our most recently enhanced version of Eeva, are further evidence of how Auxogyn is advancing reproductive health and providing clinical evidence that people can trust when making important IVF treatment decisions."
The comparative study included a total of 328 patients between the ages of 25 and 42, of which 161 elected to incorporate the Eeva results selecting embryo(s) for a day 3 transfer. Concurrently, 167 patients were enrolled for comparison and had a standard day 5 blastocyst transfer based on morphological assessment. Both groups had comparable patient clinical characteristics, number of eggs, number of embryos and number of embryos transferred.
Key findings presented at the conference indicate that the adjunct usage of Eeva with cleavage stage embryo transfer achieved implantation rates that were similar to a standard day 5 transfer (clinical pregnancy rates 42% in both groups).
"We are encouraged by these data which have had a clear impact on our clinic," stated Professor Fleming. "We now have evidence that incorporating Eeva results in the selection of embryos to transfer at Day 3 cleavage stage achieves results that are comparable with Day 5 blastocyst transfers. We believe it is a viable alternative to Day 5 blastocyst transfer, which could reduce the potential risks that may be associated with extended culture and further simplify laboratory procedures".
Auxogyn is also announcing today the launch of Eeva 2.2, which offers several new features to further assist clinicians in assessing embryo development potential and selecting the best embryo(s) to transfer.
The Eeva Test provides IVF clinicians with information about the embryo's development potential. Eeva proprietary software automatically analyzes embryo development against scientifically validated cell-division parameters conceived by researchers at Stanford University in the US. With results from the Eeva Test, IVF teams will have morphological assessment and objective information to aid their embryo selection decisions. The Eeva Test was evaluated in a prospective, multi-center, 160-patient prospective multi-center trial with ~1,800 embryos. Results of this study were presented in July 2012 at the European Society of Human Reproduction and Embryology (ESHRE) Annual Meeting and published by Conaghan et al in Fertility and Sterility, May 2013.
The Eeva Test is currently CE Marked and available for use in the EU and authorized by Health Canada for sale in Canada. The FDA submission is pending and Eeva is not available for sale in the United States. For a full list of clinics in the EU offering the Eeva Test please visit http://www.eevaivf.com.
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Auxogyn. "New clinical data on day 3 embryo transfers using Eeva™ technology presented." Medical News Today. MediLexicon, Intl., 7 Jan. 2014. Web.
24 Apr. 2014. <http://www.medicalnewstoday.com/releases/270830>
Auxogyn. (2014, January 7). "New clinical data on day 3 embryo transfers using Eeva™ technology presented." Medical News Today. Retrieved from
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