DePuy Synthes Spine, in collaboration with DePuy Synthes Biomaterials, has announced the U.S. launch of CONFORM SHEET™, a hydrated, pliable and totally demineralized cancellous bone matrix that fills voids during posterolateral spinal fusion surgery and provides a natural scaffold for new bone formation.

The new allograft implant, processed by the Musculoskeletal Transplant Foundation (MTF), has both osteoinductive1,2 and osteoconductive3 properties. Through a unique demineralization process, bone morphogenic proteins (BMPs) are exposed, providing CONFORM SHEET its osteoinductive properties, while the cancellous structure of the scaffold provides osteoconductive characteristics. CONFORM SHEET is wickable in that it readily absorbs various hydrating fluids including bone marrow aspirate, blood or saline. When combined with bone marrow aspirate, CONFORM SHEET becomes osteogenic4.

"CONFORM SHEET has excellent handling characteristics. It is compressible for precise placement, where it can then expand to fill the bone void," said Khalid Sethi, MD, FACS, Chief of Neurosurgery at United Health Services Wilson Medical Center in Johnson City, NY. "It is packaged in a hydrated state, which eliminates the need for rehydration and there is no implant migration upon irrigation."

CONFORM SHEET is offered in four sizes, which may be cut to accommodate irregular shaped anatomy. The implant may be used with DePuy Synthes Spine MATRIX™ MIS Pedicle Screw System and EXPEDIUM® Spine System, as well as other systems for spinal fusion.

DePuy Synthes Spine also offers CONFORM CUBE®*≠ Demineralized Cancellous Bone, which launched in 2011. CONFORM CUBE is another fully demineralized cancellous bone product in the form of a cube. The implant comes in five sizes and has the same properties as the CONFORM SHEET, but does not come pre-hydrated.

For more information about DePuy Synthes Spine and DePuy Synthes Biomaterials, visit http://www.depuysynthes.com.