Creating a free account will enable you to subscribe to our daily and weekly email newsletters, as well as customize your reading experience to show only the categories most relevant to you.
Signing up only take a few minutes, so why not give it a try and see what you've been missing out on.
Girls treated for Hodgkin's disease during adolescence acquire a considerable risk of developing breast cancer, as shown by an observational study published in the current issue of Deutsches Ärzteblatt International. The study, which was carried out by Günther Schellong and his colleagues in the German Working Group on the Long-Term Sequelae of Hodgkin's Disease, has an unusually long follow-up time (average 17.8 years, maximum 33 years).
The incidence figures for secondary breast cancer are based on long-term observation of 590 female patients in the German-Austrian pediatric treatment trials dating back to the years 1978 to 1995. The authors estimate that 19% of the girls treated with radiotherapy for Hodgkin's disease develop secondary breast cancer within 30 years as a result of that therapy. Because of these findings, a structured screening program for breast cancer in this high-risk group has been set up in Germany, making use of existing structures put in place by the German Consortium for Hereditary Breast and Ovarian Cancer (Deutsches Konsortium für familiären Brust- und Eierstockkrebs).
The study authors recommend that, when supradiaphragmatic radiotherapy is necessary in girls over the age of 9, the part(s) of the chest exposed to the radiation should be kept as small as medically justifiable. This will allow the risk of breast cancer to be kept as low as possible.
Breast cancer in young women after treatment for Hodgkin ́s lymphoma during childhood or adolescence - an observational study with up to 33-year follow up, Authors: Schellong G, Riepenhausen M, Ehlert K, Brämswig J, Dörffel W on behalf of the German Working Group on the Long-Term Sequelae of Hodgkin’s Disease; Schmutzler RK, Rhiem K, Bick U on behalf of the German Consortium for Hereditary Breast and Ovarian Cancer, Dtsch Arztebl Int 2014; 111(1-2): 3-9; DOI: 10.3238/arztebl.2014.0003
Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our Lymphology/Lymphedema category page for the latest news on this subject.
Please use one of the following formats to cite this article in your essay, paper or report:
International, Deutsches Aerzteblatt. "Breast cancer in young women after treatment for Hodgkin's disease during childhood or adolescence." Medical News Today. MediLexicon, Intl., 23 Jan. 2014. Web.
10 Mar. 2014. <http://www.medicalnewstoday.com/releases/271550>
International, D. (2014, January 23). "Breast cancer in young women after treatment for Hodgkin's disease during childhood or adolescence." Medical News Today. Retrieved from
Please note: If no author information is provided, the source is cited instead.
If you write about specific medications, operations, or procedures please do not name healthcare professionals by name.
For any corrections of factual information, or to contact our editorial team, please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
This page was printed from: http://www.medicalnewstoday.com/releases/271550.php
Visit www.medicalnewstoday.com for medical news and health news headlines posted throughout the day, every day.
© 2004-2014 All rights reserved. MNT (logo) is the registered trade mark of MediLexicon International Limited.