In addition to their lipid-lowering effect, statins exert anti-inflammatory and antioxidant effects as well.
Credit: Neural Regeneration Research
Statins also provide protection against renal, pulmonary and myocardial ischemia/reperfusion injury.
However, little evidence is available on similar changes in cerebral ischemia/reperfusion injury.
Therefore, Dr. Qiuyun Tu and colleagues from Third Xiangya Hospital of Central South University in China verified that atorvastatin, a commonly used lipid-lowering drug, protects against cerebral ischemia/reperfusion injury through anti-infammatory and antioxidant effects.
The relevant study has been published in Neural Regeneration Research (Vol. 9, No. 3, 2014).
Article: " Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects " by Qiuyun Tu1, Hui Cao2, Wei Zhong 2, Binrong Ding1, Xiangqi Tang1 (1 Departments of Geriatrics, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China; 2 Departments of Neurology, Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China)
Tu QY, Cao H, Zhong W, Ding BR, Tang XQ. Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects. Neural Regen Res. 2014;9(3):268-275.