Does hormonal contraception alleviate premenstrual symptoms?

The results of a new study designed to compare the severity and timing of perimenstrual symptoms among women who do or do not use cyclic hormonal contraception are reported in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Women's Health website.

The article entitled "The Influence of Cyclic Hormonal Contraception on Expression of Premenstrual Syndrome" is coauthored by Journal of Women's Health Editor-in-Chief Susan Kornstein, Executive Director of the Virginia Commonwealth University Institute for Women's Health, Richmond, VA, Kimberly Yonkers, MD and Margaret Altemus, MD, Yale University School of Medicine, and Brianna Cameron and Ralitza Gueorguieva, PhD, Yale University School of Public Health, New Haven, CT.

The researchers report changes in menstrual cycle symptom scores for variables such as depression, anger, irritability, and physical symptoms between cyclic hormonal contraception users and nonusers. They found that cyclic hormonal contraception may attenuate premenstrual symptoms, but that the timing of symptoms is similar regardless of whether the subjects used hormonal contraception. Better understanding the psychological and physical effects of hormonal contraception could help guide clinicians in the diagnosis and treatment of premenstrual syndrome (PMS).

"Because women taking hormonal contraceptives are routinely excluded from studies of PMS and premenstrual dysphoric disorder (PMDD), this study provides a valuable examination of the influence of exogenous hormones on premenstrual symptom expression and response to treatment," says Robert Downs, MD, Deputy Editor of Journal of Women's Health, Richmond, VA.

Research reported in this publication was supported by the National Institute on Mental Health under Award Number R01 MH072955, R01 MH072645, and MH072962. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Article: The Influence of Cyclic Hormonal Contraception on Expression of Premenstrual Syndrome, Yonkers Kimberly A., Cameron Brianna, Gueorguieva Ralitza, Altemus Margaret, and Kornstein Susan G, Journal of Women's Health, doi:10.1089/jwh.2016.5941, published online 17 November 2016.