Can Pigs 'catch' Avian Influenza? Defra Response, UK
Main Category: Bird Flu / Avian FluAlso Included In: Veterinary
Article Date: 04 Mar 2006 - 3:00 PDT
The risk of a pig catching avian influenza is very low. Because we are aware of the possibility we can look for it happening and deal with it if it does.
It is more likely to happen on premises where there is already infection in poultry.
We know that during the outbreak of AI in 2003 (H7N7) in the Netherlands, seropositive pigs were found on premises where birds had disease.
This means that the pigs on those premises, exposed to presumably large amounts of infected bird faeces, developed antibodies to AI.
In one case the pigs had been fed broken eggs from infected flocks. However the Dutch found no evidence of clinical disease in those pigs and no evidence of pig to pig transmission.
No AI virus was isolated from the pigs, so at the time they were sampled they were not infectious.
Pigs did not appear to play any part in the spread of disease in the Netherlands. The Dutch, sensibly, did not slaughter the pigs.
There are reports of the H5N1 AvI infections in pigs in China and Indonesia. However these infections, like the Dutch cases do not appear to be significant in the maintenance and spread of disease.
http://www.defra.gov.uk
Visit our bird flu / avian flu section for the latest news on this subject.
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Dismissive DEFRA
posted by Dr. J. N. Tristram on 4 Mar 2006 at 9:55 amSo nothing to worry about if pigs get avian flu then? This is what a viral research company says:
"In October, Recombinomic's prediction/warning was based upon H5N1 entering the Middle East via migratory birds, where another avian influenza, H9N2 was endemic. Recombinomics, utilizing its patent pending approach, predicted that the H gene in H5N1 would exchange genetic information with the H gene in H9N2 and would acquire the genetic change S227N (also called S223N). This alteration had been previously shown to increase the affinity of H5N1 for human receptors. In late December 2005, the first human infections by the Qinghai strain of H5N1 were reported in Turkey. S227N was detected in the index case for that outbreak with six additional cases confirmed four of whom
died.
Today, Recombinomics is predicting a similar change in the adjacent
position of the H5N1 virus' receptor binding domain. The donor sequences are again on the H, but in H1N1 European swine sequences. The new genetic change, G228S, has also been previously shown to increase the affinity for human receptors. Like H9N2 in the Middle East, H1N1 is endemic in swine populations in Europe. Infection by H5N1 in H1N1 infected swine will allow the viruses to exchange genetic information via recombination and allow H5N1 to acquire S228N. The region of identity between H5N1 and H1N1 is downstream from the
S227N position, so H5N1, with and without the S227N change, can acquire this new sequence. This sequence acquisition by the H5N1 virus will also lead to more efficient transmission to humans."
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