AUA 2006 - Mitochondrial Activity In Patients With Asthenozoospermia

Main Category: Urology / Nephrology
Also Included In: Fertility
Article Date: 12 Jun 2006 - 0:00 PDT

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The authors address an important and perplexing problem - asthospermia or low motility. They hypothesize that mitochondrial dysfunction of sperm may be the etiology.

Mitochondrial activity is assessed using optic microscopy. Cells were graded as grade 11 (all mitochondria alive), II (most mitochondria active), III (most inactive) and IV (all inactive). They authors data indicates that patients with asthenoozoospermia have low mitochondrial activity.

Editorial Comment:
This study may provide an explanation for asthenospermia. The question remains, "Why are the mitochondria inactive?"

Poster 1619
Mitochondrial Activity in Patients with Asthenozoospermia
B. Victorino et al

By Harris Nagler, MD

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